5 Significances of Monitoring Glycated Hemoglobin

1. The normal value of glycated hemoglobin, an indicator that reflects the overall blood sugar control of diabetic patients, is 4% to 6%. < 4% control is low and prone to hypoglycemia; 6% to 7% control is ideal; 7% to 8% is acceptable; 8%-9% means poor control; > 9% means poor control, which is a risk factor for the development of chronic complications, and acute complications such as ketoacidosis may occur, so when it > 8%, blood glucose control should be strengthened control.

 

2. It helps to understand the chronic complications of diabetes. If glycated hemoglobin > 9%, it means that the patient has persistent hyperglycemia, which will lead to complications such as diabetic nephropathy, arteriosclerosis, and cataracts. It is also a high-risk factor for death from myocardial infarction and stroke. Chen Xiaozhuan et al. reported that the increase in glycated hemoglobin is related to the occurrence, development, and prognosis of ischemic cerebral infarction. The level of glycated hemoglobin in patients with diabetic nephropathy is higher than that in patients without diabetic nephropathy, and as the level of glycated hemoglobin increases, the levels of urinary glucose lb, IgG, and NAG increase accordingly.

 

3. Guide the adjustment of blood sugar. When glycated hemoglobin is < 7.3%, postprandial blood sugar has a greater impact on glycated hemoglobin. When between 7.3% and 8.4%, fasting and postprandial blood sugar have similar effects on glycated hemoglobin. >85%, fasting blood glucose plays a more important role. Therefore, people with high glycated hemoglobin levels need to better control their fasting blood glucose levels. Therefore, those with glycated hemoglobin between 7% and 8% should intervene more in postprandial blood sugar to reduce hypoglycemic reactions; those with >8% should take into account both fasting and postprandial blood sugar; <8% should focus on improving postprandial blood sugar. In addition, since glycated hemoglobin reflects the average level over a period of time, for example, it is 6% to 7% when measured regularly, but this time > 8% indicates that the previous treatment plan cannot control blood sugar well, and a new treatment plan needs to be adjusted.

 

4. It is of certain significance to judge the different stages of diabetes. The average glycated hemoglobin is 5.6% for people with normal glucose tolerance. The average glycated hemoglobin is 6.2% for patients with isolated elevated fasting blood glucose. It is 5.9% for patients with isolated glucose intolerance. Patients with existing abnormal glucose tolerance The number of patients with elevated fasting blood glucose was 62%, and the glycated hemoglobin of newly screened diabetic patients was 8%. Therefore, glycosylated hemoglobin levels can represent different stages of prediabetes and conditions in patients with diabetes.

 

5. Distinguish detection significance between stress-induced hyperglycemia and gestational diabetes. Blood sugar increases under stress conditions such as cerebrovascular emergencies, but glycated hemoglobin does not. Measuring blood sugar alone is not enough for gestational diabetes. It is more meaningful to control glycosylated hemoglobin < 8% to avoid fetal macrosomia, stillbirth, malformation, and early stage of fetal pain. Therefore, glycated hemoglobin is an important parameter for the control of gestational diabetes.

 

In summary, the detection of glycated hemoglobin is of great significance to the overall condition of diabetic patients. Clinical medical workers cannot only manage blood sugar based on their understanding of blood sugar. They should integrate glycated hemoglobin to better control blood sugar and prevent the occurrence of complications.